The Claim

In hemodialysis patients, daily supplementation with 5 grams of creatine monohydrate over 12 months leads to an average increase of 0.8 liters in intracellular water volume, with 60% of patients showing gains, which may contribute to observed increases in fat-free mass and muscle size.

Source: Effect of Creatine Supplementation on Body Composition and Malnutrition-Inflammation Score in Hemodialysis Patients: An Exploratory 1-Year, Balanced, Double-Blind Design

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
74score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

If you're on dialysis, taking a creatine supplement every day for a year might help your muscles hold more water and get bigger, and most people in the study saw some benefit.

See the scientific wording

In hemodialysis patients, 5 grams of creatine monohydrate daily for 12 months increases intracellular water volume by approximately 0.8 liters on average, with 60% of supplemented patients showing gains, which may contribute to observed increases in fat-free mass and muscle size.

What the research says

1 study
  1. Study: Effect of Creatine Supplementation on Body Composition and Malnutrition-Inflammation Score in Hemodialysis Patients: An Exploratory 1-Year, Balanced, Double-Blind Design

    The study gave creatine to dialysis patients for a year and found their cells held more water, which helped increase muscle mass—just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.