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Strong Support

Taking creatine for 10 days might turn on a gene in young men's muscles that helps muscle cells grow and stay alive.

60
Pro
0
Against

Evidence from Studies

Supporting (1)

60

Community contributions welcome

60

Global and targeted gene expression and protein content in skeletal muscle of young men following short-term creatine monohydrate supplementation.

Randomized Controlled Trial
Human
2008 Jan 17

The study gave men the same creatine dose as in the claim and found that genes linked to muscle cell growth and survival, including one called SPHK1, increased up to 5 times, which matches the claim.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Global and targeted gene expression and protein content in skeletal muscle of young men following short-term creatine monohydrate supplementation.

Score: 60
DOI: 10.1152/PHYSIOLGENOMICS.00157.2007

Similar Assertions

Taking creatine for just a week can turn on important muscle cell signals that help with growth and energy use in young, healthy guys.

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Taking creatine for a week might change genes in young men's muscles that help reshape the muscle structure, possibly because the muscle cells are holding more water.

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