Taking creatine for a short time might turn on genes in young men's muscles that help fix DNA, possibly because the cells are reacting to the stress from holding more water.

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Global and targeted gene expression and protein content in skeletal muscle of young men following short-term creatine monohydrate supplementation.

Randomized Controlled Trial

Human

2008 Jan 17

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Global and targeted gene expression and protein content in skeletal muscle of young men following short-term creatine monohydrate supplementation.

Score: 60

DOI: 10.1152/PHYSIOLGENOMICS.00157.2007

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