Taking creatine supplements the way some athletes do—starting with a big dose, then switching to a smaller one—might temporarily boost the sugar stored in your muscles, but that boost fades once you switch to the smaller daily dose.

38

Pro

0

Against

Evidence from Studies

Supporting (1)

38

Community contributions welcome

38

Creatine supplementation increases glycogen storage but not GLUT-4 expression in human skeletal muscle.

Randomized Controlled Trial

Human

2004 Jan

The study gave people creatine the same way the claim says — a big dose first, then a small one — and found their muscles stored more sugar (glycogen) at first, but that extra sugar disappeared when they switched to the smaller dose.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Creatine supplementation increases glycogen storage but not GLUT-4 expression in human skeletal muscle.

Score: 38

DOI: 10.1042/CS20030116

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