The Claim

Creatine monohydrate supplementation at a loading dose of 25 g/day followed by 5 g/day maintenance for 21 days does not alter serum testosterone concentrations in healthy college-aged male rugby players.

Source: Three Weeks of Creatine Monohydrate Supplementation Affects Dihydrotestosterone to Testosterone Ratio in College-Aged Rugby Players

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
53score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Description
1 study reviewed
In plain English

Taking creatine monohydrate for 21 days, starting with 25 grams per day then reducing to 5 grams per day, does not change the level of testosterone in the blood of healthy male rugby players in college.

See the scientific wording

Creatine monohydrate supplementation does not alter serum testosterone concentrations in healthy college-aged male rugby players over a 21-day period, even when administered at a loading dose of 25 g/day followed by 5 g/day maintenance.

Why this might work

Creatine increases the activity of an enzyme that turns testosterone into a stronger hormone called dihydrotestosterone, so the amount of testosterone in the blood stays the same even though the stronger hormone goes up.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Three Weeks of Creatine Monohydrate Supplementation Affects Dihydrotestosterone to Testosterone Ratio in College-Aged Rugby Players

    Taking creatine for three weeks didn’t change the amount of testosterone in the blood of young male rugby players, even though another related hormone (DHT) went up. So, the claim that creatine doesn’t affect testosterone is correct.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.