The Claim

Creatine supplementation during resistance training in young men increases skeletal muscle mass and muscular cross-sectional area by approximately 10–15% over eight weeks, regardless of whether creatine monohydrate or hydrochloride is used.

Source: Supplementing With Which Form of Creatine (Hydrochloride or Monohydrate) Alongside Resistance Training Can Have More Impacts on Anabolic/Catabolic Hormones, Strength and Body Composition?

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
69score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

In young men doing resistance training, taking creatine for eight weeks results in a 10–15% increase in skeletal muscle mass and muscle cross-sectional area, whether they take creatine monohydrate or creatine hydrochloride.

See the scientific wording

Creatine supplementation during resistance training in young men likely increases skeletal muscle mass and muscular cross-sectional area by approximately 10–15% over eight weeks, independent of whether creatine monohydrate or hydrochloride is used.

Why this might work

Creatine enters muscle cells and boosts energy reserves, allowing more intense and longer workouts. This extra energy lets muscles work harder, triggering growth signals. At the same time, creatine pulls water into muscle cells, swelling them, which tells the cells to build more protein and stop breaking it down. Together, these effects cause muscles to grow larger and stronger.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Supplementing With Which Form of Creatine (Hydrochloride or Monohydrate) Alongside Resistance Training Can Have More Impacts on Anabolic/Catabolic Hormones, Strength and Body Composition?

    When young men took creatine (either kind) while lifting weights for 8 weeks, they gained about 10–15% more muscle in their arms and thighs than those who didn’t take creatine — and neither kind of creatine was better than the other.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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