The Claim
Eight weeks of resistance training combined with creatine supplementation (monohydrate or hydrochloride) in young men increases the testosterone-to-cortisol ratio, increases growth hormone and IGF-1 levels, and decreases cortisol and ACTH levels.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In young men, eight weeks of resistance training with creatine supplementation raises the testosterone-to-cortisol ratio, increases growth hormone and IGF-1, and lowers cortisol and ACTH.
See the scientific wording
Eight weeks of resistance training combined with creatine supplementation (either monohydrate or hydrochloride) in young men likely increases the testosterone-to-cortisol ratio and growth hormone and IGF-1 levels, while decreasing cortisol and ACTH, suggesting a shift toward a more anabolic hormonal environment.
Creatine builds up in muscle cells, causing them to swell with water. This swelling turns on signals that increase muscle-building hormones and turn off signals that break down muscle. More muscle-building hormones like testosterone and IGF-1 are released, while stress hormones like cortisol and ACTH drop. This change creates an environment where muscles grow bigger and stronger.
What the research says
1 studyWhen young men did weight training and took creatine for 8 weeks, their body made more of the hormones that help build muscle and less of the ones that break it down — exactly what the claim said would happen.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.