Taking a drug called exenatide for 16 weeks helps obese women who don’t have diabetes lose about 1.7 cm from their waist, even if they don’t change their diet or exercise.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Short-Term Exenatide Treatment Leads to Significant Weight Loss in a Subset of Obese Women Without Diabetes

Randomized Controlled Trial

Human

2012 Jan

The study looked at the same medicine (exenatide) in the same kind of people (obese women without diabetes) and found it reduced waist size, which supports the claim.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Short-Term Exenatide Treatment Leads to Significant Weight Loss in a Subset of Obese Women Without Diabetes

Score: 56

DOI: 10.2337/dc11-0931

Similar Assertions

Some women who are obese but don’t have diabetes lose a good amount of weight on a drug called exenatide for 16 weeks, but almost as many actually gain weight — showing it works very differently from person to person.

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Taking a drug called exenatide twice a day for about four months helps obese women who don’t have diabetes lose around 2.5 kilograms on average, and they start seeing results in just two weeks.

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Even if obese women lose weight on a drug called exenatide, their metabolism doesn’t slow down like it usually does when people lose weight from dieting — so this drug might skip the usual 'metabolic slowdown' people hit.

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