The Claim
Leucine supplementation at 7.5 g/day (2.5 g per meal) provides no additional benefit to basal muscle protein synthesis, muscle fiber growth, lean mass gain, or frailty reduction in older women already consuming optimized protein intake (1.2 g/kg/day) during resistance training.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In older women who already eat enough protein and do resistance training, taking extra leucine supplements does not improve muscle protein synthesis, muscle growth, lean mass, or reduce frailty.
See the scientific wording
Leucine supplementation at 7.5 g/day (2.5 g per meal) provides no additional benefit to basal muscle protein synthesis, muscle fiber growth, lean mass gain, or frailty reduction in older women already consuming optimized protein intake (1.2 g/kg/day) during resistance training.
When older women do strength training and eat enough protein, their muscles sense the physical stress and turn on a system that builds more muscle proteins. Adding extra leucine does not make this system work any better because the muscle already has all the signals it needs from the workout and the protein it already eats.
What the research says
1 studyIn older women who already eat enough protein and do strength training, taking extra leucine pills didn’t help them build more muscle or get stronger or less frail—just doing the workouts and eating well was enough.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.