Taking glycine and NAC for 16 weeks made older people's bodies better at using insulin than before they started taking it
Scientific Claim
Glycine and N-acetylcysteine supplementation for 16 weeks in older adults was associated with improved insulin sensitivity compared to baseline measurements
Evidence Quality Assessment
Claim Status
overstated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design (with unclear blinding) cannot establish causation. The phrase 'improved/corrected' implies causation when only association was demonstrated. The appropriate verb should indicate association rather than improvement.
More Accurate Statement
“Glycine and N-acetylcysteine supplementation for 16 weeks in older adults was associated with better insulin sensitivity compared to baseline measurements”
Source Excerpt
“Compared to YA, OA had GSH deficiency, OxS, mitochondrial dysfunction (with defective molecular regulation), inflammation, endothelial dysfunction, IR, multiple aging hallmarks, impaired physical function, increased waist circumference, and systolic blood pressure. GlyNAC (and not placebo) supplementation in OA improved/corrected these defects.”