A vitamin supplement for older adults to feel younger
Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
GlyNAC improved mitochondrial function by increasing fat burning by 78% while reducing glucose oxidation by 65%, which is counterintuitive since most people think of mitochondria as 'energy factories' that should burn more glucose.
Most people assume better metabolism means burning more glucose, but this shows the body was actually becoming more efficient at using fat for energy, which is typically associated with younger, healthier metabolism.
Practical Takeaways
Older adults with obesity might consider discussing GlyNAC supplementation with their doctor, as it improved multiple aging markers without weight loss.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
GlyNAC improved mitochondrial function by increasing fat burning by 78% while reducing glucose oxidation by 65%, which is counterintuitive since most people think of mitochondria as 'energy factories' that should burn more glucose.
Most people assume better metabolism means burning more glucose, but this shows the body was actually becoming more efficient at using fat for energy, which is typically associated with younger, healthier metabolism.
Practical Takeaways
Older adults with obesity might consider discussing GlyNAC supplementation with their doctor, as it improved multiple aging markers without weight loss.
Publication
Journal
The journals of gerontology. Series A, Biological sciences and medical sciences
Year
2022
Authors
Premranjan Kumar, Chun Liu, J. Suliburk, Jean W. Hsu, R. Muthupillai, F. Jahoor, C. Minard, G. Taffet, R. Sekhar
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Claims (10)
Taking GlyNAC for 16 weeks helps older adults with obesity make more of their body's main antioxidant in muscles and blood, bringing it up to levels normally seen in younger people.
Taking GlyNAC for 16 weeks significantly reduces markers of oxidative damage in older adults with obesity, bringing them down to levels normally seen in younger people.
Taking GlyNAC for 16 weeks helps older adults with obesity burn fat more efficiently in their mitochondria and use less glucose for energy, bringing their metabolism closer to that of younger people.
Taking GlyNAC for 16 weeks significantly reduces inflammation in older adults with obesity, bringing their inflammatory markers down to levels normally seen in younger people.
Taking GlyNAC for 16 weeks helps older adults with obesity walk faster and have stronger hands, bringing their physical abilities closer to those of younger people.