Taking GlyNAC for 16 weeks helps older adults with obesity walk faster and have stronger hands, bringing their physical abilities closer to those of younger people.
Scientific Claim
GlyNAC supplementation (100 mg/kg/day each of glycine and N-acetylcysteine) for 16 weeks in older adults with BMI >27 improved gait speed by 19% and increased grip strength by 14% in the dominant hand, restoring physical function to levels seen in young adults.
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
This is a randomized controlled trial with direct measurements of physical function before and after intervention. The study design supports causal claims about the specific outcome measured in this population.
Source Excerpt
“Only GlyNAC supplementation increased gait speed in OAG-16w to levels not different from YA-0w, increased upper and lower extremity muscle strength, with a trend toward increasing 6-minute walk distance”
Evidence from Studies
Supporting Evidence (1)
The study measured gait speed and grip strength before and after GlyNAC supplementation in older adults with BMI >27. The data shows significant improvements in gait speed and grip strength after 16 weeks of GlyNAC supplementation, with levels reaching those of young adults. Placebo group showed no improvement.