The Claim

In women aged 40-65, the addition of 30 mg hyaluronic acid to a daily supplement containing 5 g hydrolyzed collagen and 80 mg vitamin C does not result in additional improvements in dermis density, skin roughness, wrinkle severity, elasticity, or hydration over a 16-week period.

Source: The Effects of Dietary Supplementation with Collagen and Vitamin C and Their Combination with Hyaluronic Acid on Skin Density, Texture and Other Parameters: A Randomised, Double-Blind, Placebo-Controlled Trial

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
77score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

Taking hyaluronic acid alongside collagen and vitamin C does not improve skin thickness, roughness, wrinkles, elasticity, or hydration more than taking collagen and vitamin C alone in women aged 40-65 over 16 weeks.

See the scientific wording

Adding 30mg hyaluronic acid to a daily supplement of 5g hydrolyzed collagen and 80mg vitamin C does not provide additional benefits for dermis density, skin roughness, wrinkle severity, elasticity, or hydration in women aged 40-65 over 16 weeks.

Why this might work

When you eat collagen supplements, your body breaks them down into tiny pieces called peptides. These peptides travel in your blood to your skin, where they wake up skin cells (fibroblasts). These cells then make more collagen and other supportive materials, and they also block enzymes that normally break down collagen. This makes the skin thicker and smoother, and reduces wrinkles. Adding hyaluronic acid pills does not make this process work better.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: The Effects of Dietary Supplementation with Collagen and Vitamin C and Their Combination with Hyaluronic Acid on Skin Density, Texture and Other Parameters: A Randomised, Double-Blind, Placebo-Controlled Trial

    Scientists found that taking hyaluronic acid pills along with collagen and vitamin C did not improve skin density, smoothness, wrinkles, firmness, or moisture any more than taking just collagen and vitamin C alone.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.