Taking L-citrulline or citrulline malate regularly may raise levels of nitric oxide metabolites after exercise in men who train with weights, and both forms appear to have comparable effects.

In men who regularly lift weights, taking L-citrulline and citrulline malate leads to similar improvements in upper body endurance and nitric oxide metabolite levels after exercise, meaning adding malate does not provide extra performance benefits.

Taking 8 grams of citrulline malate does not change blood nitrate/nitrite levels, leg strength during high-intensity exercise, blood flow, or how efficiently the body uses energy in young men who exercise recreationally.

Taking 8 grams of L-citrulline or 12 grams of L-citrulline DL-malate daily for six weeks may help resistance-trained men perform more repetitions to failure in bench press and incline press exercises compared to taking a placebo.

Taking L-citrulline or citrulline malate supplements does not lower the levels of lactate or urea in the blood after resistance exercise in men who regularly train with weights.

Taking a specific supplement called L-citrulline every day for a week, plus a little more before working out, can boost a key chemical in your blood by about three-quarters — and that chemical helps your body make nitric oxide, which is good for blood flow.