The Claim

L-citrulline and citrulline malate supplementation do not significantly reduce post-exercise blood lactate or urea levels in resistance-trained men.

Source: Changes in resistance training performance, rating of perceived exertion, and blood biomarkers after six weeks of supplementation with L-citrulline vs. L-citrulline DL-malate in resistance-trained men: a double-blind placebo-controlled trial

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
59score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Description
1 study reviewed
In plain English

Taking L-citrulline or citrulline malate supplements does not lower the levels of lactate or urea in the blood after resistance exercise in men who regularly train with weights.

See the scientific wording

L-citrulline and citrulline malate supplementation do not significantly reduce post-exercise blood lactate or urea levels in resistance-trained men, suggesting that ammonia clearance and metabolic buffering are not primary mechanisms for their observed effects.

What the research says

1 study

  1. Study: Changes in resistance training performance, rating of perceived exertion, and blood biomarkers after six weeks of supplementation with L-citrulline vs. L-citrulline DL-malate in resistance-trained men: a double-blind placebo-controlled trial

    The study found that taking citrulline helped people lift more reps, but didn’t lower the buildup of lactate or urea in their blood—so those aren’t why citrulline works. It probably helps by improving blood flow instead.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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