The Claim

In trained cyclists, 28 days of daily quercetin supplementation (500 mg twice daily) is associated with a significant reduction in ferric reducing antioxidant power (FRAP) compared to placebo.

Source: Effects of Quercetin and Citrulline on Nitric Oxide Metabolites and Antioxidant Biomarkers in Trained Cyclists

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
75score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

In trained cyclists, taking 500 mg of quercetin twice daily for 28 days is linked to a measurable decrease in systemic antioxidant capacity as measured by FRAP, compared to a placebo.

See the scientific wording

In trained cyclists, 28 days of daily quercetin supplementation (500 mg twice daily) is associated with a significant reduction in ferric reducing antioxidant power (FRAP) compared to placebo, suggesting that quercetin may lower systemic antioxidant capacity in this population despite its theoretical antioxidant properties.

Why this might work

When quercetin is taken daily, the body senses the extra antioxidant and reduces its own natural antioxidant production, leading to lower overall antioxidant power in the blood.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Effects of Quercetin and Citrulline on Nitric Oxide Metabolites and Antioxidant Biomarkers in Trained Cyclists

    In trained cyclists, taking quercetin pills for a month made their body's antioxidant measure go down, not up — which is surprising because quercetin is supposed to help with antioxidants. The study found this drop was real and not just random.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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