The Claim

Inorganic nitrate or nitrite supplementation has no significant effect on cognitive function in adults aged 18–73.

Source: Effects of inorganic nitrate and nitrite consumption on cognitive function and cerebral blood flow: A systematic review and meta-analysis of randomized clinical trials

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
55score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Quantitative
1 study reviewed
In plain English

Taking inorganic nitrate or nitrite supplements does not change cognitive performance in adults between 18 and 73 years old.

See the scientific wording

Inorganic nitrate or nitrite supplementation does not significantly improve cognitive function in adults aged 18–73, as demonstrated by a meta-analysis of 13 randomized controlled trials involving 297 participants, with a standardized mean difference of +0.06 (95% CI: -0.06 to 0.18, P = 0.32), indicating no meaningful effect across diverse cognitive domains and supplementation protocols.

Why this might work

When inorganic nitrate is consumed, it is converted to nitrite by bacteria in the mouth, then to nitric oxide in the blood and tissues. Nitric oxide relaxes blood vessels in the brain, increasing blood flow. Despite this increase in blood flow, there is no measurable improvement in memory, attention, or other thinking skills.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Effects of inorganic nitrate and nitrite consumption on cognitive function and cerebral blood flow: A systematic review and meta-analysis of randomized clinical trials

    Scientists looked at 13 studies where people took nitrate or nitrite supplements like beetroot juice and found no improvement in memory or thinking skills. So, these supplements don’t seem to help your brain work better.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.