Giving testosterone to men over 40 who have low testosterone levels doesn't seem to make their mood or depression symptoms any better, according to this claim.

39

Pro

0

Against

Evidence from Studies

Supporting (1)

39

Community contributions welcome

39

Symptomatic benefits of testosterone treatment in patient subgroups: a systematic review, individual participant data meta-analysis, and aggregate data meta-analysis.

Systematic Review With Meta-Analysis

Human

This study looked at older men with low testosterone and gave some of them testosterone pills or shots. It found that their mood didn’t get better, even though their sex life improved. So, testosterone doesn’t help with depression in this group.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Symptomatic benefits of testosterone treatment in patient subgroups: a systematic review, individual participant data meta-analysis, and aggregate data meta-analysis.

Score: 39

DOI: 10.1016/s2666-7568(23)00169-1

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