Does low testosterone medicine help older men feel better?
Symptomatic benefits of testosterone treatment in patient subgroups: a systematic review, individual participant data meta-analysis, and aggregate data meta-analysis.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Testosterone therapy did not improve depression symptoms, despite widespread cultural belief that it does.
Many men and influencers believe low testosterone is a root cause of depression—this study directly contradicts that with data from over 5,600 men.
Practical Takeaways
If you’re a man over 40 with low testosterone and erectile issues, talk to your doctor about whether testosterone therapy might help your sexual function.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
Testosterone therapy did not improve depression symptoms, despite widespread cultural belief that it does.
Many men and influencers believe low testosterone is a root cause of depression—this study directly contradicts that with data from over 5,600 men.
Practical Takeaways
If you’re a man over 40 with low testosterone and erectile issues, talk to your doctor about whether testosterone therapy might help your sexual function.
Publication
Journal
The lancet. Healthy longevity
Year
2023
Authors
Jemma Hudson, M. Cruickshank, R. Quinton, Lorna Aucott, Frederick Wu, Mathis Grossmann, Shalender Bhasin, Peter J Snyder, Susan S. Ellenberg, T. Travison, Gerald B Brock, E. Gianatti, Y. T. van der Schouw, M. Emmelot-Vonk, Erik J Giltay, G. Hackett, Sudarshan Ramachandran, J. Svartberg, Kerry L Hildreth, Kristina Groti Antonič, J. Tenover, H. Tan, Christopher Ho Chee Kong, Wei Shen Tan, Leonard S Marks, R. J. Ross, Robert S Schwartz, Paul Manson, Stephen A Roberts, Marianne Skovsager Andersen, Line Velling Magnussen, M. Aceves-Martins, Katie Gillies, Rodolfo Hernández, N. Oliver, W. Dhillo, Siladitya Bhattacharya, M. Brazzelli, C. Jayasena
Related Content
Claims (6)
For men over 40 with low testosterone, taking testosterone supplements might slightly improve how they feel in certain areas of daily life—like energy or mood—compared to taking a sugar pill.
For men over 40 with low testosterone, taking testosterone supplements might slightly help reduce symptoms like fatigue or low mood compared to taking a sugar pill.
For men over 40 with low testosterone, taking testosterone supplements may help improve their sexual function enough to make a real difference in how they feel, compared to not taking anything.
Giving testosterone to men over 40 who have low testosterone levels doesn't seem to make their mood or depression symptoms any better, according to this claim.
If you're a man over 40 with low testosterone and you take testosterone therapy, your erectile function will improve no matter how old you are, how much you weigh, if you have diabetes, or how low your testosterone was to start — but if you're older or heavier, your overall function might still be lower than someone younger or leaner.