The Claim
Supplementation with Streptococcus salivarius M18 for 14 days has no effect on systolic, diastolic, or mean arterial blood pressure in healthy normotensive adult males, despite increasing plasma nitrite levels, indicating that elevated plasma nitrite does not result in reduced blood pressure in this population.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Taking Streptococcus salivarius M18 for 14 days increases plasma nitrite levels but does not lower blood pressure in healthy adult men with normal blood pressure.
See the scientific wording
Supplementation with Streptococcus salivarius M18 for 14 days does not reduce systolic, diastolic, or mean arterial blood pressure in healthy normotensive adult males, despite a significant increase in plasma nitrite, suggesting that nitric oxide bioavailability alone is insufficient to lower blood pressure in this population.
A probiotic bacteria in the mouth converts dietary nitrate into nitrite, which enters the bloodstream and raises nitrite levels, but this does not cause blood vessels to widen or lower blood pressure in healthy men with normal blood pressure.
What the research says
1 studyTaking this probiotic for two weeks made a blood marker related to blood vessel relaxation go up, but it didn’t lower blood pressure in healthy men. So, just boosting that marker isn’t enough to change blood pressure in people who already have normal levels.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.