Tanycytes are special cells in the brain that can create new brain cells. Bmal1 is a gene that helps keep our body's daily rhythm. When Bmal1 is turned off only in these special cells, they stop making new brain cells.
See the scientific wording
Loss of function of the Bmal1 gene specifically in tanycytes inhibits the process of neurogenesis that originates from tanycytes.
Correlational — new studies may shift this
Observational2 low-scoring studies link this claim to the outcome, but causation is not established.
What the research says
2 studies reviewedSupporting (2)
Tanycyte Bmal1 sex-specifically regulates weight gain and hypothalamic neurogenesis in female mice
Cohort StudyAnimal
Turning off Bmal1 in tanycytes stops new brain cells in female mice, but not in male mice.
Tanycyte BMAL1 regulates high-fat diet weight gain and shapes arcuate neurogenesis in female mice.
Cohort StudyAnimal2026
When the Bmal1 gene is turned off only in tanycytes, female mice make fewer new brain cells in that area, but male mice are unaffected.
Contradicting (0)
No contradicting studies found yet
That doesn't mean it's settled — it just means no study has tested the opposite.
Quality-weighted scoring: we follow the GRADE framework — each study is rated High, Moderate, Low, or Very Low based on study design, methodology rigor, and risk of bias. A single high-quality RCT can outweigh several weaker observational studies.
Scores reflect study quality, not just count.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 2 supporting studies
How Fit Body Science checks a claim
- 1
We isolate the claim
Health advice from videos, articles and studies is broken down into single, testable claims.
- 2
We find the research
Each claim is matched against peer-reviewed studies, with every source cited by DOI.
- 3
We grade the evidence
Studies are scored on methodology, statistical rigor, transparency and publication quality.
The fitness and health internet is full of confident claims. We check them against real research.
Every claim on this site is traced back to peer-reviewed studies, scored on methodology and reporting quality, and given a verdict you can audit yourself — sources, DOIs and all.
- Full evidence breakdown and mechanism chains
- Ask our AI anything about a claim or its studies
- Get notified when new research changes a verdict