The drug makes core muscles bigger and stronger while reducing the fat that sneaks into them.
Scientific Claim
Tesamorelin increases cross-sectional area and density of trunk skeletal muscles while reducing intramyocellular lipid infiltration.
Original Statement
“tessamearellin increased the area and density of key trunk muscles like in our core. So the abs, the spinal extensors, the diaphragm, the pelvic floor while muscle fat infiltration decreased.”
Context Details
Domain
pharmacology
Population
human
Subject
Tesamorelin
Action
increases muscle area and density and reduces intramyocellular lipid infiltration
Target
trunk skeletal muscles
Intervention Details
Evidence from Studies
Supporting (2)
The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV
This study found that a drug called tesamorelin made muscles bigger and denser while reducing fat inside the muscles, exactly what the claim says.
The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV
The study found that tesamorelin made trunk muscles bigger and denser, which means they likely had less fat inside them — similar to how a leaner steak is denser than one with lots of marbling.