The amount of a specific gene involved in nitrate reduction (narH) was similar in the mouths of pregnant women who later got preeclampsia and those who stayed healthy.

Scientific Claim

There was no significant difference in the abundance of the nitrate reductase subunit narH between women who developed preeclampsia and normotensive pregnant women.

Original Statement

“There was no difference in the abundance of this gene between women who developed preeclampsia and those who remained normotensive (p = 0.38, Figure 4B).”

From study:Reduced Abundance of Nitrate-Reducing Bacteria in the Oral Microbiota of Women with Future Preeclampsia

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The claim correctly states 'no significant difference' which accurately reflects the statistical finding without implying causation or mechanism.

Evidence from Studies

Supporting (1)

Reduced Abundance of Nitrate-Reducing Bacteria in the Oral Microbiota of Women with Future Preeclampsia

Case-Control Study

Human

2022 Mar 8

Contradicting (0)

No contradicting evidence found

Source Study

Reduced Abundance of Nitrate-Reducing Bacteria in the Oral Microbiota of Women with Future Preeclampsia

Score: 41

DOI: 10.3390/nu14061139

Similar Assertions

Pregnant women who later got preeclampsia ate about the same amount of nitrate-rich vegetables (like spinach and beets) as women who stayed healthy during pregnancy.

77%

Whether a woman is pregnant or not doesn't seem to affect how well her mouth bacteria can convert nitrate to nitrite.

71%