People with early Alzheimer’s who take 7 mg of rapamycin every week seem to have low levels of the drug in their blood before their next dose—so low that it probably won’t weaken their immune system.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Pharmacokinetic analysis of intermittent rapamycin administration in early-stage Alzheimer's Disease

Cohort Study

Human

The study gave Alzheimer’s patients a weekly 7 mg dose of rapamycin and found that the drug levels in their blood before the next dose were too low to cause significant immune suppression, which supports the claim.

Contradicting (0)

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No contradicting evidence found

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Source Study

Pharmacokinetic analysis of intermittent rapamycin administration in early-stage Alzheimer's Disease

Score: 44

DOI: 10.1101/2025.03.18.25324017

Similar Assertions

Taking a weekly 7 mg dose of rapamycin for early Alzheimer's doesn't vary too much from person to person, so doctors might not need to adjust doses or monitor blood levels in future studies.

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83%

For people with early Alzheimer’s taking a weekly 7 mg rapamycin pill, checking their blood 48 hours after the dose gives the most consistent results and best predicts their baseline levels—so that’s the best time to test it.

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82%

When people with early Alzheimer's take rapamycin once a week, the drug stays in their body about as long as it does in other groups — around 69 hours — which means it leaves the body at a similar rate even with weekly dosing.

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