People with early Alzheimer’s who take 7 mg of rapamycin every week seem to have low levels of the drug in their blood before their next dose—so low that it probably won’t weaken their immune system.

Taking a weekly 7 mg dose of rapamycin for early Alzheimer's doesn't vary too much from person to person, so doctors might not need to adjust doses or monitor blood levels in future studies.

For people with early Alzheimer’s taking a weekly 7 mg rapamycin pill, checking their blood 48 hours after the dose gives the most consistent results and best predicts their baseline levels—so that’s the best time to test it.

When people with early Alzheimer's take rapamycin once a week, the drug stays in their body about as long as it does in other groups — around 69 hours — which means it leaves the body at a similar rate even with weekly dosing.