When people take liraglutide for weight loss, their brain's 'decision-making' area might become more active as a way to push back against further weight loss — which could be why the pounds stop dropping after a while.

When people with obesity take a weight-loss drug called liraglutide for 5 weeks, their brain's food-reward area becomes more active when they see food — even after accounting for weight loss, which might mean the brain is fighting back against losing weight.

If someone is obese and takes a weight-loss drug called liraglutide for 5 weeks, their brain doesn’t react differently to pictures of food — at least not if we don’t factor in how much weight they lost.

If you're an obese adult, taking a daily injection of liraglutide for 5 weeks might help you lose about 2.7% more weight than if you took a fake pill, and it could also lower your blood sugar, bad cholesterol, and waist size — plus you might naturally eat less fat and fewer calories.