Giving a special drug to overweight mice on a fatty diet lowers their insulin levels by 71% and helps their bodies use insulin better—without making them lose weight.

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Evidence from Studies

Supporting (1)

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13

Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice

Cohort Study

Animal

2017 Mar 22

Scientists gave mice a special drug that stops fat breakdown in fat cells, and the mice became better at handling sugar in their blood — even without losing weight. This matches what the claim says.

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No contradicting evidence found

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Source Study

Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice

Score: 13

DOI: 10.1038/ncomms14859

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