The FDA only approved this enzyme injection for the butt, but doctors often use it on the thighs too — with a weaker solution and different injection pattern.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Collagenase Clostridium histolyticum for the Treatment of Cellulite in the Buttocks and Thigh: Early Insights From Clinical Practice

Narrative Review

2022

The study shows that doctors are already using this FDA-approved butt cellulite treatment on thighs too, using different methods — which is exactly what the claim says.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Collagenase Clostridium histolyticum for the Treatment of Cellulite in the Buttocks and Thigh: Early Insights From Clinical Practice

Score: 1

DOI: 10.1093/asjof/ojac057

Similar Assertions

The treatment causes bruising and soreness at the injection site, but these side effects are usually mild and go away within a couple of weeks.

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78%

The treatment works just as well for women with light skin as it does for women with dark skin — skin color doesn’t make a difference in how well it works.

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74%

Women who got the enzyme injection felt less self-conscious, embarrassed, or like they looked older because of their cellulite — and they were much happier with how their skin looked.

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72%

Younger, leaner women tend to see better results from the injection than older or heavier women — but even older or heavier women still benefit more than those who don’t get the treatment.

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71%