The Claim
HOXA10 expression is higher in gluteal subcutaneous adipose tissue than in abdominal subcutaneous adipose tissue in both men and women, and this elevated expression persists during in vitro adipocyte differentiation, indicating a potential association with the functional identity of gluteal adipocytes.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
The HOXA10 gene is more active in fat cells under the skin of the buttocks than in fat cells around the abdomen, and this higher activity continues even when these cells are grown in a lab. This suggests HOXA10 may help determine why gluteal fat behaves differently from abdominal fat.
See the scientific wording
HOXA10 is up-regulated in gluteal subcutaneous adipose tissue compared to abdominal fat in both men and women, and its expression is retained during in vitro adipocyte differentiation, suggesting it may play a role in maintaining the distinct functional identity of gluteal fat cells.
What the research says
1 studyStudy: Distinct developmental signatures of human abdominal and gluteal subcutaneous adipose tissue depots.
Scientists found that a gene called HOXA10 is more active in butt fat than belly fat in both men and women, and this stays true even when fat cells are grown in a lab. This suggests HOXA10 helps make butt fat different from belly fat.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
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