Strong Support
mechanistic
The IgA antibodies attacking kidney cells in IgA nephropathy specifically recognize a small region at the end of the βII-spectrin protein, called Sptbn1C, which could be used to develop precise tests...
32
0
Evidence from Studies
Supporting (1)
32
Community contributions welcome
32
Identification of IgA autoantibodies targeting mesangial cells redefines the pathogenesis of IgA nephropathy
Case-Control Study
Human & Animal & In Vitro
2023 Mar 22Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.