Tests showed that the amount of bisphenol A (BPA) in people's urine and hair was lower than the safety limits set by health agencies, suggesting no significant health risk from exposure in this group.
Mechanism
Synthesis from 1 study
Your body quickly turns BPA into a harmless substance that gets flushed out in urine, and a tiny bit gets trapped in hair as a passive trace. Because this cleanup happens so fast and completely, BPA never builds up to levels that could cause harm.
Most probable mechanism
When bisphenol A enters the body, it is quickly broken down by the liver into harmless compounds that are filtered out by the kidneys and removed in urine, and some is also stored in hair as a trace byproduct — because this process is so fast and efficient, the amount left in the body stays far below levels that could cause harm.
Bisphenol A is absorbed from the digestive tract or skin into the bloodstream.
The liver rapidly conjugates bisphenol A with glucuronic acid, converting it into a water-soluble, biologically inactive metabolite.
The conjugated metabolite is efficiently filtered by the kidneys and excreted in urine within hours of exposure.
A small fraction of unconjugated bisphenol A binds to keratin in hair follicles during growth, resulting in trace, non-bioactive deposition.
Evidence from Studies
Supporting (1)
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