quantitative
Analysis v1
Strong Support

People born with certain gene changes that lower their bad cholesterol over their whole life have a lower chance of heart disease — the more their cholesterol is lowered, the lower their risk.

59
Pro
0
Against

Evidence from Studies

Supporting (1)

59

Community contributions welcome

The study looked at people born with genetic changes in the PCSK9 gene that lower their bad cholesterol their whole life, and found the more their cholesterol was lowered, the lower their risk of heart disease — just like the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.