Consuming bone broth increases the amount of nutrients absorbed from the digestive tract because of its amino acids and minerals.
Mechanism
Synthesis from 1 study
The amino acids and minerals in bone broth repair the gut lining and stop inflammation, making the barrier tighter. This allows more nutrients from food to be absorbed into the body.
Most probable mechanism
Amino acids in bone broth repair and seal the gut lining, while minerals strengthen the barrier and reduce inflammation, allowing more nutrients to pass from the intestine into the bloodstream.
Glutamine is absorbed by intestinal cells and used as fuel to produce energy and activate signaling pathways that increase production of tight junction proteins.
Glycine and arginine reduce inflammation in the gut by blocking signals that trigger immune activation and cytokine release.
Proline and hydroxyproline are incorporated into new collagen fibers that reinforce the structural support beneath the gut lining.
Zinc activates transcription factors that increase expression of tight junction proteins and protects intestinal cells from oxidative damage.
Tight junction proteins form a continuous seal between intestinal cells, reducing leakage and improving selective transport of nutrients.
Improved barrier integrity and reduced inflammation allow more efficient uptake of dietary nutrients across the intestinal epithelium.
Evidence from Studies
Supporting (1)
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Bone Broth Benefits: How Its Nutrients Fortify Gut Barrier in Health and Disease
Contradicting (0)
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Gold Standard Evidence Needed
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