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Back to Study: Aldosterone-Sensing Neurons in the NTS Exhibit Sta...
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Analysis v1
Strong Support

The same brain cells that sense low salt also have a built-in alarm for angiotensin, a hormone that signals low blood volume—so they respond to both signals together.

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Evidence from Studies

Supporting (1)

11

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11

Aldosterone-Sensing Neurons in the NTS Exhibit State-Dependent Pacemaker Activity and Drive Sodium Appetite via Synergy with Angiotensin II Signaling.

Cohort Study
Animal
2017 Sep 27

The study shows that certain brain cells that sense low salt also respond to a hormone called angiotensin II, and when both signals are present, they make animals really crave salt—like a team-up between two warning systems.

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No contradicting evidence found

Source Study

Aldosterone-Sensing Neurons in the NTS Exhibit State-Dependent Pacemaker Activity and Drive Sodium Appetite via Synergy with Angiotensin II Signaling.

Score: 11
DOI: 10.1016/j.neuron.2017.09.014

Similar Assertions

Just turning on the salt-craving brain cells doesn't make mice eat salt fast—unless you also trigger the angiotensin signal, then they immediately start licking salt like crazy.

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It’s not just being thirsty that makes mice eat salt—only when the angiotensin signal is present does turning on salt-craving cells make them lick salt, not when they’re just dehydrated.

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84%

The salt-craving brain cells connect directly to a specific spot in the brain called the vlBNST—turning on just that connection makes mice drink salt water, even without other triggers.

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73%

If you remove most of the salt-craving brain cells, mice no longer seek out salt—even when they’re very low on it.

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