The same HIV patients with belly fat who responded to tesamorelin also saw their under-the-skin fat become denser by 3.5 points on CT scans after 26 weeks, regardless of fat amount changes, indicating healthier fat tissue.

For HIV patients with belly fat who responded to tesamorelin, the drug made the subcutaneous fat denser by 3.5 points on a CT scan scale compared to placebo, regardless of changes in fat amount.

The same drug that reduces belly fat in HIV patients also makes the fat under the skin denser and healthier-looking on scans, even when the amount of fat doesn’t change much.

For HIV patients with excess belly fat who responded to the drug tesamorelin, taking the drug for 26 weeks made the fat around their organs denser by 2.3 points on a CT scan scale, even after accounting for changes in fat amount, which suggests the fat became healthier.

In HIV patients with belly fat who responded to the drug tesamorelin, the treatment made the visceral fat denser by 2.3 points on a CT scan scale compared to placebo, even after accounting for changes in fat amount.

The fat under the skin gets denser and healthier-looking on scans even when the amount of that fat doesn’t change much — the drug is improving its quality directly.