Statins, a type of medicine that started with a scientist finding something in fungi, help prevent heart problems in people at high risk by lowering bad cholesterol in their blood.

Evidence from Studies

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Akira Endo: Father of Statins

Editorial/Opinion

2024 Aug

The study talks about how Akira Endo discovered the first statin from fungi, and how statins have helped millions of people avoid heart disease. This supports the idea that statins have reduced heart problems worldwide.

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Source Study

Akira Endo: Father of Statins

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DOI: 10.7759/cureus.68198

Similar Assertions

Statins are drugs that lower cholesterol by blocking a key enzyme in the liver, and doctors use them to help prevent heart disease — but they can cause side effects that might be worse than the benefits for some people.

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A scientist named Akira Endo thought that fungi make natural chemicals to fight off other microbes — and that idea helped create the first cholesterol-lowering statin drugs.

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This new statin, atorvastatin, lowers bad cholesterol more than older statins have been shown to in past studies.

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A scientist named Akira Endo found the first statin in a fungus back in 1971, and that discovery led to the cholesterol-lowering medicines millions of people take today.

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Taking statins to lower your 'bad' cholesterol by about 1 point (in mmol/L) can cut your risk of dying from heart problems by 12% and your overall risk of dying by 9%, without raising your risk of dying from other causes like cancer or accidents.

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