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Back to Study: Reduction of LDL cholesterol by 25% to 60% in pati...
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Analysis v1
Strong Support

This new statin, atorvastatin, lowers bad cholesterol more than older statins have been shown to in past studies.

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Pro
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Evidence from Studies

Supporting (1)

57

Community contributions welcome

57

Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor.

Randomized Controlled Trial
Human
1995 May

This study found that a drug called atorvastatin lowered bad cholesterol more than other similar drugs had before, which means it might be the best statin for lowering cholesterol so far.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor.

Score: 57
DOI: 10.1161/01.ATV.15.5.678

Similar Assertions

Taking atorvastatin every day for 6 weeks can lower 'bad' cholesterol by up to 60% in people with high cholesterol, and the higher the dose, the more it drops.

57
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87%

Atorvastatin doesn’t just lower bad cholesterol — it also lowers overall cholesterol and a key protein linked to heart disease, and higher doses make these effects stronger.

57
0
86%

Statins do not induce significant regression of established atherosclerotic plaque but reduce plaque progression and enhance plaque stability by lowering LDL cholesterol exposure to arterial walls.

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78%

Statins are drugs that lower cholesterol by blocking a key enzyme in the liver, and doctors use them to help prevent heart disease — but they can cause side effects that might be worse than the benefits for some people.

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1
77%

Even without niacin, statins alone can shrink plaque in the neck arteries of older adults with heart disease, as long as their bad cholesterol is kept low.

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76%