Lifting weights with just a few heavy reps or many lighter reps gives about the same muscle growth when you do the same total work.

When guys who’ve never lifted weights before start training, most of their strength gains come from their muscles getting bigger—not from their brain and nerves getting better at telling muscles to work harder.

You can still build muscle even if you don't push your sets to within five reps of total failure, which goes against the idea that only the last few tough reps really matter for growth.