When researchers gave insulin to healthy rats and measured how their bodies handled glucose, they found no connection between this process and the rats' blood pressure or heart rate. In other words, insulin's effect on sugar processing doesn't seem to affect heart and blood vessel measurements.

13

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0

Against

Evidence from Studies

Supporting (1)

13

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13

Seven Days of Euglycemic Hyperinsulinemia Induces Insulin Resistance for Glucose Metabolism but Not Hypertension, Elevated Catecholamine Levels, or Increased Sodium Retention in Conscious Normal Rats

Cohort Study

Animal

1997 Oct

The study kept rats with high insulin levels for 7 days while keeping blood sugar normal, then measured how their bodies handled glucose and compared it to their blood pressure and heart rate. The results showed that even though insulin's ability to process glucose got worse (reduced by 39-62%), blood pressure and heart rate didn't change at all - they're not connected.

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No contradicting evidence found

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Source Study

Seven Days of Euglycemic Hyperinsulinemia Induces Insulin Resistance for Glucose Metabolism but Not Hypertension, Elevated Catecholamine Levels, or Increased Sodium Retention in Conscious Normal Rats

Score: 13

DOI: 10.2337/diacare.46.10.1572