Scientists think a specific gene called SLC8A1 might affect how your blood pressure reacts when you eat a lot of salt, at least in people of Han Chinese descent who already have high blood pressure.

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Evidence from Studies

Supporting (1)

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Genetic Variation in SLC8A1 Gene Involved in Blood Pressure Responses to Acute Salt Loading

Cross-Sectional Study

Human

2018 Mar 10

Scientists gave people with high blood pressure a lot of salt and found that those with a certain version of the SLC8A1 gene had bigger blood pressure spikes — so yes, this gene likely plays a role in how salt affects blood pressure in this group.

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Source Study

Genetic Variation in SLC8A1 Gene Involved in Blood Pressure Responses to Acute Salt Loading

Score: 41

DOI: 10.1093/ajh/hpx179

Similar Assertions

Some people in China with high blood pressure have a specific gene change that makes their blood pressure spike even more when they eat a lot of salt.

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In people of Han Chinese descent with high blood pressure, having a specific version of a gene (rs434082 A) seems to make their blood pressure rise a little more when they eat a lot of salt, even after accounting for how much salt they’ve excreted and their age.

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