mechanistic
Analysis v1
Strong Support
In mice, certain nutrients and a gut chemical they produce can slow down the body's ability to remove cholesterol — but only if the gut bacteria are active.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis
Cohort Study
Human
2013 MayThe study shows that when mice eat nutrients like those in red meat, their gut bacteria turn them into a substance called TMAO, which makes it harder for the body to remove cholesterol. This matches the claim.
Contradicting (0)
0
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No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.