Eating too much fructose, like the sugar in soda and candy, may leak harmful substances from your gut into your blood, which can irritate your liver and contribute to clogged arteries.

From: John Yudkin’s hypothesis: sugar is a major dietary culprit in the development of cardiovascular disease

Strongly supported

Multiple high-quality studies back this claim.

1
Pro
0
Against
mechanistic
1 study

Not medical advice. For informational purposes only. Always consult a healthcare professional.

What this claim means

Eating too much fructose, like the sugar in soda and candy, may leak harmful substances from your gut into your blood, which can irritate your liver and contribute to clogged arteries.

See the technical phrasing

Excess dietary fructose is associated with increased intestinal permeability and endotoxemia, which in turn activate liver inflammation and promote the development of atherosclerosis.

What the research says

Supports

1 study

1

Study: John Yudkin’s hypothesis: sugar is a major dietary culprit in the development of cardiovascular disease

This study provides evidence supporting the claim.

Contradicts

0 studies

0

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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