The Claim
Ten weeks of endurance training in female Wistar rats enhances hepatocyte sensitivity to norepinephrine, resulting in a significant increase in gluconeogenesis at 0.5 nM norepinephrine in trained cells, whereas untrained cells require at least 2.0 nM for a significant response, indicating a leftward shift in the dose-response curve and increased hormonal sensitivity in trained liver cells.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
After 10 weeks of endurance training, female rat liver cells become more sensitive to a stress hormone called norepinephrine, meaning they start producing more sugar with much smaller amounts of the hormone compared to untrained rats.
See the scientific wording
Endurance training in female Wistar rats for 10 weeks enhances hepatocyte sensitivity to norepinephrine, with trained cells showing a significant increase in gluconeogenesis at 0.5 nM NE, while untrained cells require at least 2.0 nM NE for a significant response, indicating a leftward shift in the dose-response curve and greater hormonal sensitivity in trained liver cells.
What the research says
1 studyThe study found that liver cells from rats that did endurance training responded more strongly to low levels of a stress hormone, making more glucose than untrained rats, which matches the claim.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.