After 10 weeks of endurance training, female rat liver cells become more sensitive to a stress hormone called norepinephrine, meaning they start producing more sugar with much smaller amounts of the hormone compared to untrained rats.

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Evidence from Studies

Supporting (1)

15

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15

Enhanced glucose production in norepinephrine and palmitate stimulated hepatocytes following endurance training

Cross-Sectional Study

Animal

2024

The study found that liver cells from rats that did endurance training responded more strongly to low levels of a stress hormone, making more glucose than untrained rats, which matches the claim.

Contradicting (0)

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No contradicting evidence found

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Source Study

Enhanced glucose production in norepinephrine and palmitate stimulated hepatocytes following endurance training

Score: 15

DOI: 10.3389/fphys.2024.1514082

Similar Assertions

Liver cells from female rats that were trained for endurance produce way more sugar when triggered by a stress hormone, compared to liver cells from untrained rats — showing their bodies are better tuned to respond under stress.

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84%

In female rats that were trained for endurance, their liver cells used more lactate to make glucose when stimulated, and this extra fuel use completely explains why they made more glucose—meaning the key change was how much lactate got into the cells, not how fast the cells processed it.

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84%

Female rats that did treadmill training for 10 weeks made more glucose in their liver cells, even when resting and without hormones, compared to rats that didn’t train.

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83%