Trans women who aren't athletes and take feminizing hormones tend to gain fat and lose muscle in the first year, with muscle continuing to decrease over three years, leading to a more typically feminine body shape.

When transgender women take estrogen for a few years, their weight tends to go up a little, but when transgender men take testosterone, their weight usually stays about the same.

Even after years of hormone therapy, transgender women might still be able to do more push-ups than cisgender women on average, possibly because some strength differences stick around longer than expected.

Trans women on feminizing hormones slowly lose upper body strength over time, and after about 2 years, their push-up ability becomes similar to that of cis women.

Trans guys who aren't athletes gain noticeable muscle and strength in their first year on testosterone, and after about 3 years, their push-ups, sit-ups, and running get close to or match the average fitness levels of cis men.

For transgender women taking estrogen pills, patches, or shots for about five years, their cholesterol and fat levels in the blood don’t seem to go up or down much — even though their estrogen goes up and testosterone goes down.