mechanistic
Analysis v1
Strong Support

When a certain gene is turned off in mice, it damages the stem cells that give hair its color—but not the regular color-making cells—so the hair gradually loses pigment and turns gray or white.

13
Pro
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Against

Evidence from Studies

Supporting (1)

13

Community contributions welcome

The study shows that turning off a gene called DGUOK in mice causes their hair to grey because it damages the stem cells that make hair color, but not the color-making cells themselves. This happens because of a buildup of harmful molecules and cell death in the stem cells.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.