Mice without a certain gene have more harmful molecules in their hair color stem cells when their hair is growing, which might be why these cells get damaged.

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Evidence from Studies

Supporting (1)

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Mitochondrial deoxyguanosine kinase depletion induced ROS causes melanocyte stem cell exhaustion and hair greying

Cross-Sectional Study

Animal

2025 Jun 16

The study shows that mice without the Dguok gene have more harmful molecules called ROS in their hair stem cells, which causes the cells to die and leads to gray hair. This matches the claim.

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Source Study

Mitochondrial deoxyguanosine kinase depletion induced ROS causes melanocyte stem cell exhaustion and hair greying

Score: 11

DOI: 10.1186/s13619-025-00242-0

Similar Assertions

When a certain gene is turned off in mice, it damages the stem cells that give hair its color—but not the regular color-making cells—so the hair gradually loses pigment and turns gray or white.

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When a certain gene is turned off in hair color cells in mice, their fur starts to gray early because the cells die off — but the ones that survive can still make pigment just fine.

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Giving an antioxidant called NAC in drinking water helped slow down hair greying in mice that were genetically prone to it, possibly by reducing harmful molecules in their bodies.

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