The Claim

Cell-free extracts from Comamonas piscis BIGb0172 and Pseudomonas berkeleyensis MSPm1 contain approximately 25–27 nM of vitamin B12 per OD unit, which is significantly higher than the vitamin B12 concentration in extracts from other wild-isolated bacterial strains tested, as determined by the growth response of E. coli B834 (DE3).

Source: A simple, fast and inexpensive approach using E. coli to detect and estimate vitamin B12 content in microbial extracts

What the research says

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Quantitative
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In plain English

Cell-free extracts from two specific bacterial strains, Comamonas piscis BIGb0172 and Pseudomonas berkeleyensis MSPm1, contain about 25–27 nanomoles of vitamin B12 per unit of optical density, a level higher than that found in extracts from other wild bacterial strains tested using E. coli B834 (DE3) growth as a measurement.

See the scientific wording

Cell-free extracts from Comamonas piscis BIGb0172 and Pseudomonas berkeleyensis MSPm1 contain significantly higher levels of vitamin B12 (approximately 25–27 nM per OD unit) than extracts from other wild-isolated bacterial strains tested, as measured by E. coli B834 (DE3) growth response.

Why this might work

Certain bacteria produce large amounts of vitamin B12, which gets released into their surroundings. When these bacterial extracts are added to a special type of E. coli that cannot make its own methionine without B12, the vitamin B12 enters the cells and activates an enzyme that makes methionine. This allows the E. coli to divide and multiply, and the more B12 present, the more the bacteria grow. The amount of growth directly reflects how much B12 was in the original extract.

Verified mechanismbased on 1 study

What the research says

1 study

  1. Study: A simple, fast and inexpensive approach using E. coli to detect and estimate vitamin B12 content in microbial extracts

    Scientists used a special E. coli that needs vitamin B12 to grow to measure how much B12 different bacteria make. They found that two types of bacteria from worms make way more B12 than others, just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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