Using a common antibacterial mouthwash for a week can increase sugar and lactic acid levels in saliva, which might make it easier for tooth decay to develop.

Scientific Claim

Chlorhexidine mouthwash (0.2%) significantly increases salivary lactate and glucose levels in healthy adults after 7 days of use, which may contribute to oral health deterioration.

Original Statement

“Furthermore, an increase in nitrate (p < 0.018), lactate (p = 0.029) and glucose (p < 0.001) was observed in the CHX-M group compared to baseline.”

From study:The comparative effect of propolis and chlorhexidine mouthwash on oral nitrite-producing bacteria and blood pressure regulation

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

definitive

Can make definitive causal claims

Assessment Explanation

This is a randomized controlled trial with direct measurement of salivary lactate and glucose levels before and after intervention. The p-values of 0.029 and <0.001 indicate statistical significance, supporting definitive language for these specific quantitative findings.

Evidence from Studies

Supporting (1)

The comparative effect of propolis and chlorhexidine mouthwash on oral nitrite-producing bacteria and blood pressure regulation

Randomized Controlled Trial

Human

2025

Contradicting (0)

No contradicting evidence found

Source Study

The comparative effect of propolis and chlorhexidine mouthwash on oral nitrite-producing bacteria and blood pressure regulation

Score: 67

DOI: 10.1080/20002297.2024.2439636

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