Using a common antibacterial mouthwash for a week can lower ammonia levels in saliva, which might make it harder for the mouth to maintain a healthy environment.

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

definitive

Can make definitive causal claims

Assessment Explanation

This is a randomized controlled trial with direct measurement of salivary ammonia levels before and after intervention. The p-value of <0.001 indicates strong statistical significance, supporting definitive language for this specific quantitative finding.

More Accurate Statement

“Chlorhexidine mouthwash (0.2%) significantly reduces salivary ammonia levels in healthy adults after 7 days of use, which may contribute to oral health deterioration.”

Evidence from Studies

Supporting (1)

The comparative effect of propolis and chlorhexidine mouthwash on oral nitrite-producing bacteria and blood pressure regulation

Randomized Controlled Trial

Human

2025

Contradicting (0)

No contradicting evidence found

Source Study

The comparative effect of propolis and chlorhexidine mouthwash on oral nitrite-producing bacteria and blood pressure regulation

Score: 67

DOI: 10.1080/20002297.2024.2439636

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