In rats with an underactive thyroid, giving vitamin D helped protect their livers, but it didn’t fix their thyroid hormone levels — meaning the liver benefits probably happened for other reasons.

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Evidence from Studies

Supporting (1)

16

Community contributions welcome

16

Vitamin D alleviates hypothyroidism associated liver dysfunction: Histological and biochemical evidence

Randomized Controlled Trial

Animal

2023 Aug

The study gave vitamin D to rats with low thyroid function and found their liver health improved, even if their thyroid levels didn’t get better. This supports the idea that vitamin D helps the liver on its own.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Vitamin D alleviates hypothyroidism associated liver dysfunction: Histological and biochemical evidence

Score: 16

DOI: 10.1016/j.heliyon.2023.e18860

Similar Assertions

In rats with an underactive thyroid, taking vitamin D every day for 6 weeks seemed to help protect their liver — especially at higher doses.

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89%

In rats with an underactive thyroid, taking vitamin D every day for 6 weeks seemed to help protect their liver from damage caused by harmful molecules, based on certain lab tests.

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86%

In rats with an underactive thyroid, taking higher-dose vitamin D for six weeks seemed to reduce scarring in the liver more than a lower dose — kind of like turning down the body’s scar-healing response in the liver.

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86%

Rats with a drug-induced underactive thyroid show signs of liver damage, including more oxidative stress and scarring, compared to healthy rats.

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73%