mechanistic
Analysis v1
Strong Support
Vitamin D helps calm inflammation in certain immune cells by stopping a specific switch in the cell’s DNA from turning on a molecule that causes inflammation.
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
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1,25-Dihydroxyvitamin D Promotes Negative Feedback Regulation of TLR Signaling via Targeting MicroRNA-155–SOCS1 in Macrophages
Case-Control Study
Animal
2013 Apr 1Vitamin D helps calm down inflammation in immune cells by blocking a specific DNA switch that would otherwise turn on a trouble-making molecule called miR-155. This switch is right inside a gene called bic, and vitamin D stops a protein (NF-κB) from activating it.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.